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Study Links Common Medications to Brain Shrinkage and Dementia

You would think that widely used medications for colds and allergies – including many that are available without a prescription – would be relatively harmless. According to a growing body of research, they are anything but.

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If it doesn’t have side effects, it isn’t a drug, so goes the saying.

But you would think that widely used medications for colds and allergies – including many that are available without a prescription – would be relatively harmless.

According to a growing body of research, they are anything but.

A class of drugs called anticholinergics have been linked to cognitive impairment in past studies, and new research provides more evidence of an association.

The new study, published in JAMA Neurology, found that older people who regularly took at least one anticholinergic drug showed poorer cognition, lower brain volumes and less glucose metabolism in the whole brain and the temporal lobe, (which is important for memory) than people who didn’t report taking this kind of medications. The link persisted even after the team controlled for the number of medications the people in the study were taking.

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